143days until
BOSS in Leuven

In the literature

The M7x-series in the literature
 
 
 

Different academic studies have proven the efficiency of our catalysts on various substrates.

Here are a few examples.

 

 

- Total synthesis of herbarumin I (Synlett, 2010, 1223)

 

 

 

In this study Dr. Debendra K. Mohapatra et al. from the Indian Institute of Chemical Technology tested the efficiency of different ruthenium-based catalysts on the synthesis of herbarumin I (a mycoherbicide).

 

The  results detailed in the graph below show a remarkable efficiency of our catalysts :

- in very little time compared to the classical Hoveyda and Grubbs catalysts,

- at room temperature instead of 40°C,

- at a noticeably lower loading,

- and with a better yield. 

 

 
 
This suggests novel stereoselective total syntheses of herbarumin I and stagonolide A, which are pharmacologically active compounds.

 

 

 

- Synthesis through Cross Metathesis

(from Angewandte Chemie International Edition, 2010, 49, 1-7)

 

 

 

 

Cross metathesis is a simple way to join two molecular blocks to build new compounds. 

Dr. M. J. Barrel et al. from the University of Edinburgh operated a catalyst screening for the reaction above and found out that the M71-SIMes gave the best results.

 

 

- Other scientific articles

 

The following articles show various applications of our catalysts and their efficiency:

 

1/  Chem Commun, 2007, (36), 3771-3773
2/  JOC, 2008, 4225-4228
3/  Chemistry Today, 2008, 26(5), 89-92
4/  Eur J. Org. Chem, 2009, 25, 4254-4265

5/  Chemistry Today
, 2009, 27(3), 20-24
6/  Chemistry Today
, 2009, 27(5), 74-78
7/  Beilstein J. Org. Chem. 2010, 6, 1159–1166